Based on these experimental results, a suitable mathematical theory has been developed that incorporates the effect of microsphere size distribution and polymer degradation on drug release. 依据这些试验结果,结合了微球大小和聚合物降解度对于药物释放的作用得到了相应的数学上的结论。
Hyperbranched Poly ( Amine-Ester) and Its Modified Polymer as Drug Carrier 超支化聚(胺&酯)及其改性聚合物作为药物载体的研究
Chromatographic column: the most commonly used filler of chromatographic column is chemically bonded silica gel. Application of temperature sensitive polymer in drug delivery system 色谱柱最常用的色谱柱填充剂为化学键合硅胶。温敏型凝胶用聚合物及在药剂学中的应用
A new polymer drug eluting stent coated with sirolimus effects on the inhibition of intimal hyperplasia 一种新型聚合物携带雷帕霉素洗脱血管支架抑制内膜增生的效应
Polymer micelle is a novel drug delivery system, formed from amphiphilic polymer by self-assembling. 聚合物胶束是一种新型的给药系统,由两亲性聚合物在选择性溶剂中自组装形成。
The design and synthesis of macromolecular prodrugs, choice of polymer carrier, active drug and linker are introduced. 对大分子前药的设计与合成,载体、活性药物和连接基的选择进行了论述。
Preparation and Application of Multifunctional Polymer Drug Carriers 多功能聚合物药物载体的制备及应用
The design and study of polymer materials used as drug controlled release devices have been reviewed, specifically the characteristics of main biodegradable polymers were evaluated and compared. 由于天然多糖作为药物控制释放材料具有比合成聚合物更多的优势,因而一直是国内外学者研究的重点。
Current situation of new type of polymer micelle drug carrier research in China 新型药物载体聚合物胶束在我国研究的现状
Application of temperature sensitive polymer in drug delivery system 温敏型凝胶用聚合物及在药剂学中的应用
The Study of Polymer Drug Film of Preparation and Mechanics Property 医用高分子药膜的制备及力学性能的研究
The effect of the size, surface area and porosity of particles, the property and content of drugs, as well as the properties of polymer on the drug release behavior of microcapsules are elucidated. 阐述了高分子包囊的粒径、表面积、孔度、药物性能和药含量,以及高分子包囊材料的性能对药物释放行为的影响。
A Review of the Application of Smart Polymer in New Drug Delivery Systems 功能高分子在新型给药系统中的应用
While NVP was incorporated into polymer drug, it had little effect on release in acid condition, but drug release rate in base condition increased markedly. 同时,共聚物中亲水组分&NVP的引入,对酸性条件下的释放影响不大,但明显加快了药物在碱性条件下释放。
This paper reviewed the type and characteristic of polymer drug controlled release materials; 本文综述了高分子药用控释材料的性能、分类及其应用;
The classification, preparation and the factors that influence the release behavior of the biodegradable polymer drug film are reviewed in this paper, providing references for the research and development of preparation of biodegradable drug film. 综述了可生物降解聚合物药物膜的组成、制备方法及其药物释放行为的影响因素,为可生物降解聚合物药物膜的研究开发提供参考。
Controlled release microspheres of glipizide were prepared by spray drying of polymer solutions containing the drug and other additives. 为研究口服药物控释微球的制备及其体外释药性质,以格列吡嗪为模型药物,采用喷雾干燥法制备具有恒速释药性质的微球。
Polymer Nanoparticles for Drug Delivery System 聚合物纳米粒子用于给药载体
In this paper we discuss mechanisms of controlled drug delivery systems and examine progress in polymer materials for controlled drug release were discussed. 综述了聚合物药物控制释放机理及其在换膜、口服、注射、植入等领域的研究进展。
Progress in Research on Polymer Materials for Controlled Drug Release 聚合物药物控制释放体系研究进展
Polymer nanoparticles as drug carriers exhibit good targeting and controlled release. 载药聚合物纳米粒具有良好的组织靶向性和缓控释性。
Studies on Synthesis and Controlled-release of Polymer Drug Using Lactic Acid-Phosphate Copolymer as Drug Carriers 乳酸-磷酸酯共聚物为载体的高分子药物的合成及其控释研究
Applications of High Molecular Polymer in Sustained-and Controlled-release Drug Delivery Systems 缓控释给药系统中高分子聚合物的应用
Biodegradable polymer micelles as drug carriers and control drug release technique by assembled micelles 可生物降解聚合物纳米胶囊型药物载体及组合胶囊的药物控制释放
Studies on Cationic Graft Polymer Micelles as Drug Delivery Systems 阳离子嫁接物胶团药物传递系统研究
Antitumour polymer drug conjugate ⅰ. synthesis of a new type of drug carriers 抗癌缀合药物研究Ⅰ.新型药物载体聚酰胺-胺型化合物的合成
The Advance of Biodegradable Polymer Drug Film 可降解聚合物药物膜的研究进展
Microspheres are a delivery system with polymer materials as drug carriers, the drug dissolves or dissipates in the polymer matrix material to form small spherical entities, which can protect the drug or control drug release. The microspheres belong to ground-substance skeleton material microparticle. 微球是指药物溶解或者分散在高分子材料基质中形成的微小球状实体,从而对药物起到保护、控制释放等作用,属于基质型骨架微粒。
Its structure includes polymer carrier, active drug, spacer and targeting moiety. 其结构主要包括:大分子载体、小分子活性药物、连接基和定位基。
Moreover, it is another key to choose a pH responsive polymer as drug carrier for this intelligent drug delivery system. 此外,选取合适的pH敏感高分子材料作为药物载体是设计和制备这种智能给药系统的另一关键。